Characterization of the bla KPC-2 and bla KPC-3 genes and the novel bla KPC-15 gene in Klebsiella pneumoniae
نویسندگان
چکیده
منابع مشابه
Detection of bla KPC-2 in Proteus mirabilis in Brazil.
INTRODUCTION Infections caused by Klebsiella pneumoniae carbapenemase (KPC)-producing isolates pose a major worldwide public health problem today. METHODS A carbapenem-resistant Proteus mirabilis clinical isolate was investigated for plasmid profiles and the occurrence of β-lactamase genes. RESULTS The isolate exhibited resistance to ertapenem and imipenem and was susceptible to meropenem, ...
متن کامل1 Role of IS Kpn 7 and deletions in bla KPC gene expression 2 3
“Revised AAC00334-12” 1 Role of ISKpn7 and deletions in blaKPC gene expression 2 3 Thierry Naas*, Gaelle Cuzon, Ha-Vy Truong, and Patrice Nordmann 4 5 Service de Bactériologie-Virologie, INSERM U914: « Emerging Resistance to Antibiotics », 6 Hôpital de Bicêtre, Assistance Publique-Hôpitaux de Paris, 94275 Le Kremlin-Bicêtre, 7 Faculté de Médecine, Université Paris-Sud, France 8 9 10
متن کاملEvaluation of the New NucliSENS EasyQ KPC Test for Rapid Detection of 1 Klebsiella pneumoniae Carbapenemase Gene ( bla
*Corresponding author: 17 Teresa Spanu 18 Istituto di Microbiologia 19 Università Cattolica del Sacro Cuore 20 Largo Gemelli, 8 21 00168 – Rome (Italy) 22 Tel: +39 06 30154218; Fax: +39063051152 23 e-mail: [email protected] 24 Copyright © 2012, American Society for Microbiology. All Rights Reserved. J. Clin. Microbiol. doi:10.1128/JCM.00284-12 JCM Accepts, published online ahead of print on ...
متن کاملMultiplex real-time PCR assay for detection and classification of Klebsiella pneumoniae carbapenemase gene (bla KPC) variants.
Carbapenem resistance mediated by plasmid-borne Klebsiella pneumoniae carbapenemases (KPC) is an emerging problem of significant clinical importance in Gram-negative bacteria. Multiple KPC gene variants (bla(KPC)) have been reported, with KPC-2 (bla(KPC-2)) and KPC-3 (bla(KPC-3)) associated with epidemic outbreaks in New York City and various international settings. Here, we describe the develo...
متن کاملIn vivo multiclonal transfer of bla(KPC-3) from Klebsiella pneumoniae to Escherichia coli in surgery patients.
During active surveillance at the Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT, Palermo, Italy) with the CARBA screening medium, five pairs of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae and Escherichia coli strains were isolated in each of five colonized patients. In each patient, lateral gene transfer was demonstrated by comparin...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2014
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.073841-0